Werkwelt

Shepherdess London Fairwell — party checklist · April 15, 2026

Working draft for the goodbye celebration at Shepherdess Walk. Treat this as the shared playbook so production, hospitality, and invites stay aligned.

🔔 RSVP and guest management: Luma guest list 💌

Foundations

• Lock the warehouse layout: guest flow, quiet room, cloak, mezzanine headcount, and emergency exit sign-off.
• Submit noise notice to Islington Council and loop in adjacent flats; file every approval in the shared folder.
• Finalize hospitality map: chef partner, welcome sip, midnight reset menu, vegan and gluten-free covered.

Atmosphere

• Design lighting: halo rigs on the mezzanine, projection reel of Werkwelt builds, live camera feed on loop.
• Build sound architecture: DJ rotation, speech handoff, 01:00 down-tempo playlist, and written dB guardrails.
• Draft run of show backbone (90 minutes): arrivals -> founder toast -> live build reveal -> gratitude segment -> finale drop.

Delivery

• Publish team roster: door lead, two floor captains, tech lead, runner pool, shift sheet, and WhatsApp broadcast list.
• Confirm capture and press: photo and video crew, instant selects wall, post-event Dropbox package template.
• Lock cleanup plan: crew booked, waste removal timing, final walkthrough checklist before returning keys.

Invites (wave one)

• Brent Hoberman - anchor for the London tech slate.
• Thomas Heatherwick - design gravity for the room.
• Reserve slots for founders, artists, and civic partners once final floorplan cap is confirmed.

Friday (from 5:00pm onward)

• Dinner-first plan, then one late stop for the after-move.
• Note Annabel's context: Julio Bruno and Vlad Guber are both out of town.
• Keep night music option flexible: SPACE WALK vs Sunil's thing based on energy.
• Magician Vincent confirmed; hold Sam the Clown (+44 7540 075833) and Bark/Gumtree/Freelancer leads for supplement.
• Gareth Fowler (Django guitar) booked: two 1-hour sets, PA included, GBP 375 solo or GBP 650 with vocals. Venmo deposit to @Gareth-Fowler-1 for a 19:00-19:30 start, cash settle night-of.
• Staffing locked: two bar staff via Greg's contact plus Vincent and Gareth confirmed.
• Schedule 16:00 walkthrough for a final readiness check of the salon.
• Send rolling reminders: text 1000 people to lock arrivals.

Add photos, budget line items, and the RSVP tracker once floorplan + council approvals are final.

Cure51 deck feedback synthesis — Laura + Amol · April 8, 2026

Combined notes from Laura’s deck-clarity edits and Amol’s investor narrative draft, merged into one tech-VC-facing post.

Laura said

• Reduce text density and open with a clear executive summary before details.
• Lead with the three proof pillars: unique dataset, engaged network, and signed pharma economics.
• Use the “my mom understands it” test for slide clarity before adding AI/process detail.
• Reference slides “Why Cure51?” and “Where new biology emerges: Outliers vs. Controls.” as anchor slides.
• Dutch phrase: Dat is glashelder. (“That is crystal clear.”)

Amol said

Cure51.com monopolizes cancer supersurvivor data to power pharma’s models.

Most of oncology is built on studying why patients die. Cure51 studies why some survive.

Our biobank is ingesting virtually all survivors globally on the deadliest cancers: PDAC, GBM, and Small Cell Lung Cancer — sourced from agreements with 600 apex academic medical centers in 55 countries and characterized at single-cell resolution. This dataset is proprietary, compounding, and structurally irreplicable. Only we have this.

The platform is already generating results. Novel targets have been validated in vitro in pancreatic cancer. A first pharma partnership has been executed on glioblastoma. Small Cell Lung Cancer is now in sequence. $5mm this year from a large EU pharma with upsize to 5x across more targets, plus up to $440mm in tail on that first program.

Backed by Sofinnova and LifeX, we are raising our $20mm Series A to expand indication cohorts, advance validated targets, deepen pharma partnerships, and build a first-in-class therapeutics pipeline rooted in the biology of exceptional survival. The future is in our data.

Synthesis — tight 10-page Series A deck spine

1. Title / one-line thesis: “The irreplicable supersurvivor data platform powering next-generation oncology discovery.”
2. Why now: oncology has failure data but poor survival intelligence; the new winner owns exceptional-survivor data at global scale.
3. The insight: compare outlier survivors vs matched controls (PDAC, GBM, SCLC) at clinical + molecular + single-cell depth.
4. The data moat: ~600 centers / 55 countries, rare-patient access, compounding dataset, structurally hard to recreate.
5. Platform logic: network effects in data ingestion and target confidence; software-like learning loop with biotech monetization.
6. Proof: PDAC targets + validation, GBM pharma program live, SCLC in sequence; initial economics established.
7. Business model: pharma partnerships + internal pipeline + platform expansion.
8. Why we win: first-mover position in rare, fragmented biological assets; relationship moat compounds via execution.
9. Series A use of funds: expand cohorts, advance targets, deepen BD, build therapeutics operating stack.
10. Big outcome: category leader for exceptional-survival biology with durable data advantage.

Slide-writing rules from synthesis

• Keep sequence strict: problem → insight → moat → platform logic → proof → business model → scale story.
• Do not lead with dense mechanism diagrams, a standalone AI slide, giant workflow art, or acronym-heavy opening slides.
• Keep the monopoly logic understandable before scientific depth.

Data requests to harden investor version

1. Exact signed centers and active countries (current count).
2. Exact sample counts by PDAC / GBM / SCLC.
3. Precise scope/wording of the first pharma deal.
4. Targets identified vs targets validated to date.
5. Exact operational definition of “virtually all survivors globally.”
6. Team-slide facts: founder story, scientific leadership, and BD credibility.

Dutch phrase: Dit wordt een scherpe deck. (“This will become a sharp deck.”)